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  <xsd:element id="clbs_AccruedGrantFunding" name="AccruedGrantFunding" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="clbs_AggregateIntrinsicValueWarrantsOutstanding" name="AggregateIntrinsicValueWarrantsOutstanding" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="clbs_AggregateIntrinsicValueWarrantsvested" name="AggregateIntrinsicValueWarrantsvested" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="clbs_AggregateIntrinsicValueWarrantsvestedandexpectedtovest" name="AggregateIntrinsicValueWarrantsvestedandexpectedtovest" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="clbs_AmortizationOfAccruedGrantFundingLiabilityToOffsetExpense" name="AmortizationOfAccruedGrantFundingLiabilityToOffsetExpense" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="clbs_BusinessTextBlock" name="BusinessTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_ChangeinOwnershipinSubsidiary" name="ChangeinOwnershipinSubsidiary" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="clbs_CommonStockWarrantsShares" name="CommonStockWarrantsShares" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="clbs_DocumentAndEntityInformationAbstract" name="DocumentAndEntityInformationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_FundingOfGrantAwardCashReceived" name="FundingOfGrantAwardCashReceived" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="clbs_H.C.WainwrightSalesAgreementMember" name="H.C.WainwrightSalesAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="clbs_H.C.WainwrightSalesAmendedAgreementMember" name="H.C.WainwrightSalesAmendedAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_IncreaseDecreaseInAccountsPayableAccruedExpensesAndOtherLiabilities" name="IncreaseDecreaseInAccountsPayableAccruedExpensesAndOtherLiabilities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="clbs_IschemicRepairCD34CellTechnologyMember" name="IschemicRepairCD34CellTechnologyMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_LesseeOperatingLeaseBalanceSheetPresentationTableTextBlock" name="LesseeOperatingLeaseBalanceSheetPresentationTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_MarketCapitalizationUsedInNetOperatingLossAnalysis" name="MarketCapitalizationUsedInNetOperatingLossAnalysis" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="clbs_MilestonePaymentOnGrantAwardCashReceived" name="MilestonePaymentOnGrantAwardCashReceived" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="clbs_NetOperatingLossAnalysisAnnualLimitation" name="NetOperatingLossAnalysisAnnualLimitation" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="clbs_NumberOfOfficesUnderOperatingLeases" name="NumberOfOfficesUnderOperatingLeases" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="clbs_OptionsVestedweightedAverageRemainingContractualTerm" name="OptionsVestedweightedAverageRemainingContractualTerm" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_PreferredStockSharesDesignated" name="PreferredStockSharesDesignated" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="instant" />
  <xsd:element id="clbs_ProgressPaymentOnGrantAwardCashReceived" name="ProgressPaymentOnGrantAwardCashReceived" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="clbs_ResearchFundingAbstract" name="ResearchFundingAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_SaleOfStockAggregateOfferingAmountAuthorizedPerAgreement" name="SaleOfStockAggregateOfferingAmountAuthorizedPerAgreement" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="clbs_SaleOfStockCommissionOnGrossProceedsDueToThirdPartyUponPercent" name="SaleOfStockCommissionOnGrossProceedsDueToThirdPartyUponPercent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_SaleOfStockMaximumNumberOfSharesAuthorizedPerAgreement" name="SaleOfStockMaximumNumberOfSharesAuthorizedPerAgreement" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="instant" />
  <xsd:element id="clbs_Sharesvestedandexpectedtovest" name="Sharesvestedandexpectedtovest" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="clbs_StockOptionsActivityAxis" name="StockOptionsActivityAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="clbs_StockOptionsActivityDomain" name="StockOptionsActivityDomain" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="clbs_UsEquityPlanMember" name="UsEquityPlanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WarrantsCanceled" name="WarrantsCanceled" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WarrantsExercised" name="WarrantsExercised" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WarrantsExpired" name="WarrantsExpired" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WarrantsGranted" name="WarrantsGranted" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WarrantsVested" name="WarrantsVested" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="clbs_WarrantsWeightedAverageExercisePriceRollForward" name="WarrantsWeightedAverageExercisePriceRollForward" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WeightedAverageExercisePriceWarrantsCanceled" name="WeightedAverageExercisePriceWarrantsCanceled" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WeightedAverageExercisePriceWarrantsExercisable" name="WeightedAverageExercisePriceWarrantsExercisable" nillable="true" substitutionGroup="xbrli:item" type="us-types:perUnitItemType" xbrli:periodType="instant" />
  <xsd:element id="clbs_WeightedAverageExercisePriceWarrantsExercised" name="WeightedAverageExercisePriceWarrantsExercised" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WeightedAverageExercisePriceWarrantsExpired" name="WeightedAverageExercisePriceWarrantsExpired" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WeightedAverageExercisePriceWarrantsGranted" name="WeightedAverageExercisePriceWarrantsGranted" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WeightedAverageExercisePriceWarrantsOutstanding" name="WeightedAverageExercisePriceWarrantsOutstanding" nillable="true" substitutionGroup="xbrli:item" type="us-types:perUnitItemType" xbrli:periodType="instant" />
  <xsd:element id="clbs_WeightedAverageExercisePriceWarrantsvestedexpectedtovest" name="WeightedAverageExercisePriceWarrantsvestedexpectedtovest" nillable="true" substitutionGroup="xbrli:item" type="us-types:perUnitItemType" xbrli:periodType="instant" />
  <xsd:element id="clbs_WeightedAverageRemainingContractualTermWarrantsVestedandExpecttoVest" name="WeightedAverageRemainingContractualTermWarrantsVestedandExpecttoVest" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WeightedAverageRemainingContractualTermwarrantoutstanding" name="WeightedAverageRemainingContractualTermwarrantoutstanding" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="clbs_WeightedAverageRemainingContractualTermwarrantsvested" name="WeightedAverageRemainingContractualTermwarrantsvested" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
</xsd:schema>
