Statement of Comprehensive Income [Abstract] Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Available for sale securities - net unrealized income (loss) Other Comprehensive Income (Loss), Securities, Available-for-Sale, Unrealized Holding Gain (Loss) Arising During Period, after Tax Total other comprehensive income (loss) Other Comprehensive Income (Loss), Net of Tax Comprehensive loss Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest Comprehensive income (loss) attributable to noncontrolling interests Comprehensive Income (Loss), Net of Tax, Attributable to Noncontrolling Interest Comprehensive loss attributable to Caladrius Biosciences, Inc. common stockholders Comprehensive Income (Loss), Net of Tax, Attributable to Parent Share-based Compensation [Abstract] Schedule Share-based Compensation Expense Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Schedule of Total Compensation Cost Related to Nonvested Awards Disclosure of Share-based Compensation Arrangements by Share-based Payment Award [Table Text Block] Schedule of Fair Value of Share-based Compensation Awards Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Equity [Abstract] Schedule of Stock by Class [Table] Schedule of Stock by Class [Table] Sale of Stock [Axis] Sale of Stock [Axis] Sale of Stock, Name of Transaction [Domain] Sale of Stock [Domain] Lincoln Park Agreement [Member] Lincoln Park Agreement [Member] Lincoln Park Agreement [Member] H.C. Wainwright Sales Amended Agreement [Member] H.C. Wainwright Sales Amended Agreement [Member] H.C. 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available for sale Investments, Fair Value Disclosure Assets, fair value disclosure Assets, Fair Value Disclosure Statement of Financial Position [Abstract] ASSETS Assets [Abstract] Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Marketable securities Marketable Securities Prepaid and other current assets Prepaid Expense and Other Assets, Current Total current assets Assets, Current Property and equipment, net Property, Plant and Equipment, Net Other assets Other Assets, Noncurrent Total assets Assets LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities and Equity [Abstract] Liabilities Liabilities [Abstract] Accounts payable Accounts Payable, Current Accrued liabilities Accrued Liabilities, Current Total current liabilities Liabilities, Current Other long-term liabilities Other Liabilities, Noncurrent Total liabilities Liabilities Commitments and Contingencies Commitments and Contingencies Stockholders' Equity Stockholders' Equity Attributable to Parent [Abstract] Preferred stock, authorized, 20,000,000 shares Series B convertible redeemable preferred stock liquidation value, 0.001 share of common stock, $0.01 par value; 825,000 shares designated; issued and outstanding, 10,000 shares at September 30, 2019 and December 31, 2018, respectively Preferred Stock, Value, Issued Common stock, $0.001 par value, authorized 500,000,000 shares; issued and outstanding, 10,411,010 and 9,865,735 shares at September 30, 2019 and December 31, 2018, respectively Common Stock, Value, Issued Additional paid-in capital Additional Paid in Capital Treasury stock, at cost; 11,080 shares at September 30, 2019 and December 31, 2018 Treasury Stock, Value Accumulated deficit Retained Earnings (Accumulated Deficit) Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax Total Caladrius Biosciences, Inc. stockholders' equity Stockholders' Equity Attributable to Parent Noncontrolling interests Stockholders' Equity Attributable to Noncontrolling Interest Total stockholders' equity Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest Liabilities and Equity, Total Liabilities and Equity Leases [Abstract] Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Balance Sheet Location [Axis] Balance Sheet Location [Axis] Balance Sheet Location [Domain] Balance Sheet Location [Domain] Other Assets [Member] Other Assets [Member] Accrued Liabilities [Member] Accrued Liabilities [Member] Other Long-Term Liabilities [Member] Other Noncurrent Liabilities [Member] Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Balance Sheet Captions Assets and Liabilities, Lessee [Abstract] Right-of-use assets Operating Lease, Right-of-Use Asset Operating lease liabilities, current Operating Lease, Liability, Current Operating lease liabilities, noncurrent Operating Lease, Liability, Noncurrent Operating lease liabilities Operating Lease, Liability Schedule of Stockholders' Equity Note, Stock Options and warrants [Table] Class of Warrant or Right [Table] Stock Options Activity [Axis] Stock Options Activity [Axis] Stock Options Activity [Axis] Stock Options Activity [Domain] Stock Options Activity [Domain] Stock Options Activity [Domain] US Equity Plan [Member] US Equity Plan [Member] US Equity Plan [Member] Award Type [Axis] Award Type [Axis] Award Type [Domain] Equity Award [Domain] Stock Options and Warrants [Line Items] Class of Warrant or Right [Line Items] Stock Options Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest [Abstract] Options, Outstanding [Roll Forward] Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Options, Outstanding, Beginning of Period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Options, Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures Options, Exercised (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Options, Forfeited (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Options, Expired (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period Options, Outstanding, End of Period (in shares) Options, Outstanding, Weighted Average Exercise Price [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Options, Outstanding. Beginning of Period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Options, Granted (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Options, Exercised (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Options, Forfeited (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Options, Expired (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Options, Outstanding, End of Period (in dollars per share) Options, Outstanding, Weighted Average Remaining Contractual Term Share-based Compensation 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Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Options, Vested (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Options, Vested, Weighted Average Exercise Price (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price Options, Vested, Weighted Average Remaining Contractual Term Options, Vested, weighted Average Remaining Contractual Term Options, Vested, weighted Average Remaining Contractual Term Options, Vested, Aggregate Intrinsic Value Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value Warrants Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, 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Exercisable Warrants, Vested, Weighted Average Remaining Contractual Term weighted Average Remaining Contractual Term, warrants vested weighted Average Remaining Contractual Term, warrants vested Warrants, Vested, Aggregate Intrinsic Value Aggregate Intrinsic Value, Warrants vested Aggregate Intrinsic Value, Warrants vested Document and Entity Information [Abstract] Document and Entity Information [Abstract] Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Shell Company Entity Shell Company Entity Current Reporting Status Entity Current Reporting Status Document Type Document Type Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal 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investing activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Purchase of marketable securities Payments to Acquire Marketable Securities Sale of marketable securities Proceeds from Sale and Maturity of Marketable Securities Proceeds from CFC device sale Proceeds from Sale of Furniture and Fixtures Acquisition of property and equipment Payments to Acquire Property, Plant, and Equipment Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Investing Activities Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Proceeds from exercise of options Proceeds from Stock Options Exercised Tax withholding payments on net share settlement equity awards Payments Related to Tax Withholding for Share-based Compensation Net proceeds from issuance of common stock Proceeds from Issuance or Sale of Equity Repayment of notes payable Repayments of Notes Payable Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Net increase (decrease) in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Cash, cash equivalents and restricted cash at beginning of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Cash and cash equivalents at end of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Supplemental Disclosure of Cash Flow Information: Supplemental Cash Flow Information [Abstract] Cash paid during the period for: Interest Paid, Including Capitalized Interest, Operating and Investing Activities [Abstract] Interest Interest Paid, Excluding Capitalized Interest, Operating Activities Finance Minimum Lease Payments Finance Lease Liabilities, Payments, Due [Abstract] 2019 Lessee, Operating Lease, Liability, Payments, 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Operating loss Operating Income (Loss) Other income (expense): Nonoperating Income (Expense) [Abstract] Investment income, net Other Nonoperating Income (Expense) Interest expense Interest Expense Total other income (expense), net Nonoperating Income (Expense) Net loss Less - net income (loss) attributable to noncontrolling interests Income (Loss) from Continuing Operations, Net of Tax, Attributable to Noncontrolling Interest Net (loss) income attributable to Caladrius Biosciences, Inc. common stockholders Net Income (Loss) Available to Common Stockholders, Basic Basic and diluted loss per share Earnings Per Share, Basic and Diluted, Other Disclosures [Abstract] Caladrius Biosciences, Inc. common stockholders (in usd per share) Earnings Per Share, Basic and Diluted Weighted average common shares outstanding Weighted Average Number of Shares Outstanding, Diluted [Abstract] Basic and diluted shares Weighted Average Number of Shares Outstanding, Basic and Diluted Subsidiary or Equity 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Securities, Available-for-sale, Fair Value, Fiscal Year Maturity [Abstract] Less than one year Debt Securities, Available-for-sale, Maturity, Remainder of Fiscal Year, Fair Value Greater than one year Debt Securities, Available-for-sale, Maturity, Allocated and Single Maturity Date, Rolling after One Through Five Years, Fair Value Total estimated fair value Debt Securities, Available-for-sale The Business The Business [Text Block] The Business [Text Block] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Restricted Stock Units (RSUs) [Member] Restricted Stock Units (RSUs) [Member] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of 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Available-for-sale, Accumulated Gross Unrealized Gain, before Tax Gross Unrealized Losses Debt Securities, Available-for-sale, Accumulated Gross Unrealized Loss, before Tax Estimated Fair Value Number of restricted stock issued Stock Issued During Period, Shares, Restricted Stock Award, Gross Value of restricted stock issued Stock Issued During Period, Value, Restricted Stock Award, Gross Weighted average estimated fair value of restricted stock issued Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Vesting terms (years) Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Fair Value Measurements Fair Value Disclosures [Text Block] Statement of Stockholders' Equity [Abstract] Statement [Table] Statement [Table] Statement, Equity Components [Axis] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Total Caladrius Biosciences, Inc. Stockholders' Equity Parent [Member] Series B Convertible Preferred Stock Preferred Stock [Member] Common Stock Common Stock [Member] Additional Paid in Capital Additional Paid-in Capital [Member] Accumulated Other Comprehensive Loss AOCI Attributable to Parent [Member] Accumulated Deficit Retained Earnings [Member] Treasury Stock Treasury Stock [Member] Non- Controlling Interest in Subsidiary Noncontrolling Interest [Member] Class of Stock [Axis] Class of Stock [Axis] Class of Stock [Domain] Class of Stock [Domain] Series B Convertible Preferred Stock Series B Preferred Stock [Member] Statement [Line Items] Statement [Line Items] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Beginning Balance (shares) Shares, Outstanding Beginning Balance Adoption of accounting standard New Accounting Pronouncement or Change in Accounting Principle, Effect of Adoption, Quantification Unrealized gain on marketable securities Other Comprehensive Income (Loss), Securities, Available-for-sale, Adjustment, after Tax Share-based compensation (in shares) Stock Issued During Period, Shares, Share-based Compensation, Net of Forfeitures Share-based compensation Stock Issued During Period, Value, Share-based Compensation, Net of Forfeitures Net proceeds from issuance of common stock (in shares) Net proceeds from issuance of common stock Stock Issued During Period, Value, New Issues Proceeds from option exercises (in shares) Proceeds from option exercises Stock Issued During Period, Value, Stock Options Exercised Change in ownership in subsidiary Change in Ownership in Subsidiary Change in Ownership in Subsidiary Ending Balance (shares) Ending Balance Preferred stock, shares authorized Preferred Stock, Shares Authorized Preferred stock, Series B convertible redeemable preferred stock liquidation value, share of common stock Convertible Preferred Stock, Shares Issued upon Conversion Preferred stock, par value (in usd per share) Preferred Stock, Par or Stated Value Per Share Preferred stock, shares designated Preferred stock, shares designated Preferred stock, shares designated Preferred stock, shares issued Preferred Stock, Shares Issued Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Common stock, par value (in usd per share) Common Stock, Par or Stated Value Per Share Common stock, shares authorized Common Stock, Shares Authorized Common stock, shares issued Common Stock, Shares, Issued Common stock, shares, outstanding Common Stock, Shares, Outstanding Treasury stock (shares) Treasury Stock, Shares Share-Based Compensation Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Loss Per Share Earnings Per Share [Text Block] Schedule of Accrued Liabilities Schedule of Accrued Liabilities [Table Text Block] Income Tax Disclosure [Abstract] Operating Loss Carryforwards [Table] Operating Loss Carryforwards [Table] Income Tax Authority [Axis] Income Tax Authority [Axis] Income Tax Authority [Domain] Income Tax Authority [Domain] Federal [Member] Domestic Tax Authority [Member] Operating Loss Carryforwards [Line Items] Operating Loss Carryforwards [Line Items] Operating loss carryforwards Operating Loss Carryforwards Market capitalization used in net operating loss analysis Market Capitalization Used In Net Operating Loss Analysis Market Capitalization Used In Net Operating Loss Analysis Annual limitation on usage of net operating losses Net Operating Loss Analysis, Annual Limitation Net Operating Loss Analysis, Annual Limitation Income Taxes Income Tax Disclosure [Text Block] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Commitments and Contingencies Disclosure [Abstract] Contingencies Commitments and Contingencies Disclosure [Text Block]